Developed for St. George’s University of London
Sudden arrhythmic death syndrome (SADS) is a sudden, unexpected death in apparently healthy, young people where the underlying cause cannot be identified, see [1]. Sudden deaths are commonly attributed to cardiac abnormalities. Myocardial fibrosis, which includes an excess amount of collagen in the myocardial tissue, is a structural abnormality that may represent underlying cardiomyopathy causing sudden deaths, see [2]. Picrosirius red (PSR) is a stain that is commonly used to visualize collagen, see [3].
This APP is used for quantifying the amount of collagen, myocardial tissue, and fatty tissue in slides. It is also capable of detecting vessels in order to exclude them from the subsequent analysis so that they do not contribute to the outputs.