Microscopic colitis is a type of inflammation of the colon that causes chronic non-bloody watery diarrhea. The disorder cannot be detected using normal colonoscopy, but is possible to detect by examining a biopsy of the colon tissue. Microscopic colitis can be distinguished into two subtypes, lymphocytic and collagenous. This APP addresses collagenous colitis, which is characterized by a thick layer of collagen in the colon tissue.
Thus, by quantifying the percentage of collagen in the colon tissue, a diagnosis can be determined.
Van Gieson, Collagenous Colitis
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