Breast cancer development and progression could be affected by its tumour-associated macrophages (TAMs). More specifically, a disbalance between TAM subtypes: M1-like and M2-like macrophages might lead to unfavourable outcome.
The present APP works on serial section TMAs stained with CD68 and CD163. The APP quantifies the number of positive cells for both stains, which enables the calculation of the M2/M1 ratio as #CD163/(#CD68 – #CD163).
CD68 & CD163, Breast Cancer, TME
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