The inducible isoform of cyclooxygenase-2 (COX2) is upregulated during both inflammation and cancer, and is described to modulate cell proliferation and apoptosis mainly in solid tumors.
The “10133 – COX2, Melanoma, TME” APP detects nuclei and classifies them as either negative, 1+, 2+ or 3+ based on the COX2 staining expression present in each nucleus’ vicinity.