Epidermal thickness, and the content of collagen/elastin in the dermal layer, and the relationship to age, gender, skin type, pigmentation, blood content, smoking habits and body site is important in dermatologic research. The epidermal thickness is often affected during skin diseases, such as psoriasis, and its measurement can therefore be a relevant parameter in the assessment of disease progression and treatment effect.
The thickness of the epidermis can vary substantially even within a tissue section. For this reason, the arithmetic mean thickness is estimated as the epidermis area divided by the length of the epidermis.
Orcein Staining, Skin
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