Developed for Medical College of Wisconsin
Centronuclear myopathy is a disease group characterized by the location of nuclei in the center of skeletal muscle fibers instead of the normal peripheral location. Symptoms of the disease include muscle weakness and diminished muscle tone.
This APP analyzes H&E stained skeletal muscle tissue to detect muscle fibers and nuclei located centrally within the fibers. The APP calculates the proportion of fibers with centronuclear myocytes.