Developed for metastasis detection in cytokeratin stained lymph nodes
Tumor staging, diagnosis, and treatment choices depend, for most cancer types, on the size of the primary tumor and whether it has metastasized to regional lymph nodes. Lymph node metastasis can be identified using a pancytokeratin (PCK) stain as a cytoplasmatic marker, coloring them brown.
The APP identifies cytokeratin positive cells and calculates the diameter or area, of the largest tumor. Images can easily be sorted based on their size, e.g. listing them in descending order.