Angiogenesis, or neovascularization, is the formation of new blood vessels originating from the endothelium of existing vasculature. Angiogenesis is known to play an important role in the neoplastic progression leading to metastasis. CD31 immunohistochemistry (IHC), is widely used in experimental studies quantifying tumor neovascularization in immunocompromised animal models implanted with transformed human cell lines.
By using this APP, neovascularization can be quantified from full virtual slides.